Pegaferon® (Peginterferon alfa-2a) is a recombinant human protein (MW 19 kDa) conjugated to monomethoxy polyethylene glycol (PEG) for a total MW of about 60 kDa. Interferon alfa-2a is produced biosynthetically using recombinant DNA technology and is the product of a cloned human leukocyte interferon gene inserted into and expressed in E coli. Purified IFN has 165 amino acids and a molecular mass of 19237.
All activities are performed in a full cGMP environment, meeting the highest international quality standards. Pooyesh Darou sterile manufacturing facility includes an 11000 sq. ft. production site. Our aseptic fill and finish manufacturing facilities are capable of filing over 13 million low volume parenteral sterile unit per year and utilizes five high-speed filling lines and two lyophilizers.